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News & Press: Clinical News

Plasma Lipoprotein(a) Concentration Predicts Future Coronary and Cardiovascular Events in Patients

Wednesday, November 13, 2013   (0 Comments)
Posted by: Sandra Tremulis
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Plasma Lipoprotein(a) Concentration Predicts Future Coronary and Cardiovascular Events in Patients With Stable Coronary Heart Disease

Paul J. Nestel, Elizabeth H. Barnes, Andrew M. Tonkin, John Simes, Marion Fournier, Harvey D. White, David M. Colquhoun, Stefan Blankenberg, David R. Sullivan+ Author AffiliationsFrom the Lipoprotein and Atherosclerosis Laboratory, Baker IDI Heart & Diabetes Institute, Melbourne, Australia (P.J.N.); NHMRC Clinical Trials Centre, University of Sydney, Sydney, Australia (E.H.B., J.S., M.F.); Department of Epidemiology & Preventative Medicine, Monash University, Melbourne, Australia (A.M.T.); Green Lane Cardiovascular Research Unit, Auckland City Hospital, Auckland, New Zealand (H.D.W.); Department of Medicine, University of Queensland, Brisbane, Australia (D.M.C.); Department of General and Interventional Cardiology, University Heart Centre Hamburg, Hamburg, Germany (S.B.); and Royal Prince Alfred Hospital Department of Biochemistry, Sydney, Australia (D.R.S.) Correspondence to Paul J. Nestel, Baker IDI Heart & Diabetes Institute, 75 Commercial Rd, Melbourne, Victoria 3004, Australia. E-mail


Conclusions—In the LIPID study, baseline Lp(a) was associated with future cardiovascular disease and CHD events. Increased Lp(a) concentrations after 1 year were also associated with future events, supporting measurement of Lp(a) for risk assessment of patients with known CHD.

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